Santana will feature as what Activision calls an unlockable "in-game artist," meaning the guitarist's image will be seen on screen as you play along to the Santana music, which, in this case, is the classic No One To Depend On, from the band's self-titled third album released in 1971.

"We're thrilled to showcase one of the top guitarists of all time in Guitar Hero 5 and offer fans the opportunity to experience Carlos Santana's signature sounds and iconic likeness first-hand," said Tim Riley, Vice President Of Music Affairs for Guitar Hero. - more on this story

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