House Party 5: Tonight's the Night continues the House Party franchise with a new crew of high school students, including Chris (Tequan Richmond) and Dylan (Zac Goodspeed). Chris thinks he has everything worked out and under control as he plans to leave high school behind and cruise to college in his brand new car.

The problem is, he'll be leaving behind his best friend and partner-in-rhyme, Dylan, and still hasn't expressed his feeling for Autumn (Tristin Mays), the girl he's had a crush on since second grade. His only solution is to throw one last party where he and Dylan can show off their skills with words and women. Chaos ensues and a little get-together becomes a hilariously epic disaster where anything can happen and anyone might turn up, including the original house partiers, Kid 'n Play.